Headcanon: Ryuko has a phobia of syringes and hypodermic needles. (Based on EP02.)

“Mikisugi-san, is the removal of your clothes necessary at all during this medical examination?”

“I thought this would help take Ryuko-kun’s mind off the injection…But it seems your method of keeping her still is much more effective, Lady Satsuki.”

“She’s going to throw me aside and run away any second now…”